A new hypoxia inducible factor-2 inhibitory pyrrolinone alkaloid from roots and stems of Piper sarmentosum.

Bokesch, Heidi Rose; Gardella, Roberta Scott; Rabe, Daniel Christopher; Bottaro, Donald Paul; Linehan, William Marston; McMahon, James Brislin; McKee, Tawnya Carlene

Bokesch, Heidi Rose; Gardella, Roberta Scott; Rabe, Daniel Christopher; Bottaro, Donald Paul; Linehan, William Marston; McMahon, James Brislin; McKee, Tawnya Carlene.

Affiliation

Bokesch HR; SAIC-Frederick, Inc., NCI-Frederick, Frederick, MD 21702, USA.

Chem Pharm Bull (Tokyo) ; 59(9): 1178-9, 2011.

Article in En | MEDLINE | ID: mdl-21881266

Subject(s)

Alkaloids/chemistry; Basic Helix-Loop-Helix Transcription Factors/antagonists & inhibitors; Piper/chemistry; Pyrroles/chemistry; Alkaloids/isolation & purification; Alkaloids/toxicity; Basic Helix-Loop-Helix Transcription Factors/metabolism; Cell Line, Tumor; Humans; Magnetic Resonance Spectroscopy; Molecular Conformation; Plant Roots/chemistry; Plant Stems/chemistry; Pyrroles/isolation & purification; Pyrroles/toxicity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrroles / Piper / Alkaloids / Basic Helix-Loop-Helix Transcription Factors Limits: Humans Language: En Journal: Chem Pharm Bull (Tokyo) Year: 2011 Type: Article Affiliation country: United States

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