Quantification of the glycine transporter 1 in rhesus monkey brain using [18F]MK-6577 and a model-based input function.

Sanabria-Bohórquez, Sandra M; Joshi, Aniket D; Holahan, Marie; Daneker, Lori; Riffel, Kerry; Williams, Mangay; Li, Wenping; Cook, Jacquelynn J; Hamill, Terence G

Sanabria-Bohórquez, Sandra M; Joshi, Aniket D; Holahan, Marie; Daneker, Lori; Riffel, Kerry; Williams, Mangay; Li, Wenping; Cook, Jacquelynn J; Hamill, Terence G.

Affiliation

Sanabria-Bohórquez SM; Imaging, Merck Research Laboratories, West Point, PA 19486, USA.

Neuroimage ; 59(3): 2589-99, 2012 Feb 01.

Article in En | MEDLINE | ID: mdl-21930214

Subject(s)

Brain Chemistry/physiology; Brain/diagnostic imaging; Excitatory Amino Acid Agonists; Glycine Plasma Membrane Transport Proteins/metabolism; Algorithms; Animals; Corpus Striatum/diagnostic imaging; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists/pharmacokinetics; Fluorine Radioisotopes; Glycine Plasma Membrane Transport Proteins/analysis; Image Processing, Computer-Assisted; Macaca mulatta; Models, Neurological; Models, Statistical; Positron-Emission Tomography; Receptors, N-Methyl-D-Aspartate/physiology; Thalamus/diagnostic imaging

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain / Brain Chemistry / Excitatory Amino Acid Agonists / Glycine Plasma Membrane Transport Proteins Type of study: Guideline / Risk_factors_studies Limits: Animals Language: En Journal: Neuroimage Journal subject: DIAGNOSTICO POR IMAGEM Year: 2012 Type: Article Affiliation country: United States

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