Cysteinyl leukotrienes impair hypoxic pulmonary vasoconstriction in endotoxemic mice.

Petersen, Bodil; Austen, K Frank; Bloch, Kenneth D; Hotta, Yukako; Ichinose, Fumito; Kanaoka, Yoshihide; Zapol, Warren M

Petersen, Bodil; Austen, K Frank; Bloch, Kenneth D; Hotta, Yukako; Ichinose, Fumito; Kanaoka, Yoshihide; Zapol, Warren M.

Affiliation

Petersen B; Department of Anesthesia and Critical Care, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.

Anesthesiology ; 115(4): 804-11, 2011 Oct.

Article in En | MEDLINE | ID: mdl-21934409

Subject(s)

Endotoxemia/physiopathology; Hypoxia/physiopathology; Leukotrienes/pharmacology; Pulmonary Circulation/drug effects; Vasoconstriction/drug effects; Animals; Bronchi/drug effects; Bronchoalveolar Lavage Fluid/cytology; Glutathione Transferase/metabolism; Hemodynamics/drug effects; Hemodynamics/physiology; Leukocyte Count; Leukotrienes/metabolism; Mice; Mice, Inbred C57BL; Neutrophils/drug effects; Neutrophils/enzymology; Organ Size/drug effects; Oxygen Consumption/drug effects; Peroxidase/metabolism; Receptors, Leukotriene/drug effects

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vasoconstriction / Leukotrienes / Pulmonary Circulation / Endotoxemia / Hypoxia Limits: Animals Language: En Journal: Anesthesiology Year: 2011 Type: Article Affiliation country: United States

Fulltext

XML

PubMed Links

Search on Google