Focal adhesion kinase signaling mediates acute renal injury induced by ischemia/reperfusion.

Qin, Yu; Alderliesten, Maaike C; Stokman, Geurt; Pennekamp, Petra; Bonventre, Joseph V; de Heer, Emile; Ichimura, Takaharu; de Graauw, Marjo; Price, Leo S; van de Water, Bob

Qin, Yu; Alderliesten, Maaike C; Stokman, Geurt; Pennekamp, Petra; Bonventre, Joseph V; de Heer, Emile; Ichimura, Takaharu; de Graauw, Marjo; Price, Leo S; van de Water, Bob.

Affiliation

Qin Y; Division of Toxicology, Leiden/Amsterdam Center for Drug Research, Leiden University, Leiden, The Netherlands.

Am J Pathol ; 179(6): 2766-78, 2011 Dec.

Article in En | MEDLINE | ID: mdl-21982831

Subject(s)

Acute Kidney Injury/enzymology; Focal Adhesion Protein-Tyrosine Kinases/metabolism; Reperfusion Injury/enzymology; Signal Transduction/physiology; Animals; Cell Adhesion/physiology; Cytokines/biosynthesis; Enzyme Inhibitors/pharmacology; Focal Adhesion Protein-Tyrosine Kinases/antagonists & inhibitors; Focal Adhesion Protein-Tyrosine Kinases/deficiency; Hydrogen Peroxide/pharmacology; Kidney Tubules, Proximal/enzymology; MAP Kinase Signaling System/physiology; Male; Mice; Mice, Knockout; Nephritis/enzymology; Oxidants/pharmacology; Oxidative Stress/physiology; Tamoxifen/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Reperfusion Injury / Signal Transduction / Focal Adhesion Protein-Tyrosine Kinases / Acute Kidney Injury Type of study: Prognostic_studies Limits: Animals Language: En Journal: Am J Pathol Year: 2011 Type: Article Affiliation country: Netherlands

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