The interface between catalytic and hemopexin domains in matrix metalloproteinase-1 conceals a collagen binding exosite.

Arnold, Laurence H; Butt, Louise E; Prior, Stephen H; Read, Christopher M; Fields, Gregg B; Pickford, Andrew R

Arnold, Laurence H; Butt, Louise E; Prior, Stephen H; Read, Christopher M; Fields, Gregg B; Pickford, Andrew R.

Affiliation

Arnold LH; Division of Molecular Structure, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, United Kingdom.

J Biol Chem ; 286(52): 45073-82, 2011 Dec 30.

Article in En | MEDLINE | ID: mdl-22030392

Subject(s)

Matrix Metalloproteinase 1/chemistry; Binding Sites/physiology; Collagen/chemistry; Collagen/genetics; Collagen/metabolism; Crystallography, X-Ray; Humans; Matrix Metalloproteinase 1/genetics; Matrix Metalloproteinase 1/metabolism; Protein Structure, Secondary; Protein Structure, Tertiary; Structure-Activity Relationship

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Matrix Metalloproteinase 1 Limits: Humans Language: En Journal: J Biol Chem Year: 2011 Type: Article Affiliation country: United kingdom

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