HIV-1 glycoprotein 41 ectodomain induces activation of the CD74 protein-mediated extracellular signal-regulated kinase/mitogen-activated protein kinase pathway to enhance viral infection.

Zhou, Chang; Lu, Lu; Tan, Suiyi; Jiang, Shibo; Chen, Ying-Hua

Zhou, Chang; Lu, Lu; Tan, Suiyi; Jiang, Shibo; Chen, Ying-Hua.

Affiliation

Zhou C; Laboratory of Immunology, School of Life Sciences, Tsinghua University, Beijing 100084, China.

J Biol Chem ; 286(52): 44869-77, 2011 Dec 30.

Article in En | MEDLINE | ID: mdl-22039051

Subject(s)

Antigens, Differentiation, B-Lymphocyte/metabolism; HIV Envelope Protein gp41/metabolism; HIV Infections/metabolism; HIV-1/physiology; Histocompatibility Antigens Class II/metabolism; MAP Kinase Signaling System; Virus Replication/physiology; Antigens, Differentiation, B-Lymphocyte/genetics; Cell Line; HIV Envelope Protein gp41/antagonists & inhibitors; HIV Envelope Protein gp41/genetics; HIV Infections/drug therapy; HIV Infections/genetics; Histocompatibility Antigens Class II/genetics; Humans; Peptides/genetics; Peptides/metabolism; Peptides/pharmacology; Protein Structure, Secondary; Protein Structure, Tertiary; Virus Replication/drug effects

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Virus Replication / Antigens, Differentiation, B-Lymphocyte / Histocompatibility Antigens Class II / HIV Envelope Protein gp41 / HIV Infections / HIV-1 / MAP Kinase Signaling System Limits: Humans Language: En Journal: J Biol Chem Year: 2011 Type: Article Affiliation country: China

Fulltext

XML

PubMed Links

Search on Google