In vivo neuronal function of the fragile X mental retardation protein is regulated by phosphorylation.

Coffee, R Lane; Williamson, Ashley J; Adkins, Christopher M; Gray, Marisa C; Page, Terry L; Broadie, Kendal

Coffee, R Lane; Williamson, Ashley J; Adkins, Christopher M; Gray, Marisa C; Page, Terry L; Broadie, Kendal.

Affiliation

Coffee RL; Department of Biological Sciences, Kennedy Center for Research on Human Development, Vanderbilt University, Nashville, TN 37232, USA.

Hum Mol Genet ; 21(4): 900-15, 2012 Feb 15.

Article in En | MEDLINE | ID: mdl-22080836

Subject(s)

Fragile X Mental Retardation Protein/metabolism; Neurons/metabolism; Animals; Animals, Genetically Modified; Brain/cytology; Brain/metabolism; Brain/pathology; Cytoskeleton/metabolism; Cytoskeleton/pathology; Disease Models, Animal; Drosophila Proteins/metabolism; Drosophila melanogaster/genetics; Drosophila melanogaster/growth & development; Drosophila melanogaster/metabolism; Fragile X Mental Retardation Protein/genetics; Fragile X Syndrome/genetics; Fragile X Syndrome/metabolism; Humans; Learning/physiology; Microtubule-Associated Proteins/metabolism; Mutation; Neuromuscular Junction/metabolism; Neuromuscular Junction/pathology; Neurons/pathology; Phosphorylation; Phosphoserine/metabolism; Protein Biosynthesis; Serine/genetics; Serine/metabolism; Transgenes

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Fragile X Mental Retardation Protein / Neurons Limits: Animals / Humans Language: En Journal: Hum Mol Genet Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2012 Type: Article Affiliation country: United States

Fulltext

XML

PubMed Links

Search on Google