Effects of the CETP inhibitor evacetrapib administered as monotherapy or in combination with statins on HDL and LDL cholesterol: a randomized controlled trial.

Nicholls, Stephen J; Brewer, H Bryan; Kastelein, John J P; Krueger, Kathryn A; Wang, Ming-Dauh; Shao, Mingyuan; Hu, Bo; McErlean, Ellen; Nissen, Steven E

Nicholls, Stephen J; Brewer, H Bryan; Kastelein, John J P; Krueger, Kathryn A; Wang, Ming-Dauh; Shao, Mingyuan; Hu, Bo; McErlean, Ellen; Nissen, Steven E.

Affiliation

Nicholls SJ; Cleveland Clinic Coordinating Center for Clinical Research, Cleveland Clinic, Cleveland, OH 44195, USA. nichols1@ccf.org

JAMA ; 306(19): 2099-109, 2011 Nov 16.

Article in En | MEDLINE | ID: mdl-22089718

Subject(s)

Benzodiazepines/administration & dosage; Cholesterol Ester Transfer Proteins/antagonists & inhibitors; Cholesterol, HDL/drug effects; Cholesterol, LDL/drug effects; Dyslipidemias/drug therapy; Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & dosage; Aged; Atorvastatin; Benzodiazepines/pharmacology; Cardiovascular Diseases/prevention & control; Double-Blind Method; Drug Therapy, Combination; Female; Fluorobenzenes/administration & dosage; Heptanoic Acids/administration & dosage; Humans; Male; Middle Aged; Pyrimidines/administration & dosage; Pyrroles/administration & dosage; Rosuvastatin Calcium; Simvastatin/administration & dosage; Sulfonamides/administration & dosage; Treatment Outcome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzodiazepines / Hydroxymethylglutaryl-CoA Reductase Inhibitors / Dyslipidemias / Cholesterol Ester Transfer Proteins / Cholesterol, HDL / Cholesterol, LDL Type of study: Clinical_trials Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: JAMA Year: 2011 Type: Article Affiliation country: United States

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