Pyruvate and creatine prevent oxidative stress and behavioral alterations caused by phenylalanine administration into hippocampus of rats.

Berti, Simone Luisa; Nasi, Guilherme Marmontel; Garcia, Cristina; Castro, Fernanda Luz de; Nunes, Michely Lopes; Rojas, Denise Bertin; Moraes, Tarsila Barros; Dutra-Filho, Carlos Severo; Wannmacher, Clóvis Milton Duval

Berti, Simone Luisa; Nasi, Guilherme Marmontel; Garcia, Cristina; Castro, Fernanda Luz de; Nunes, Michely Lopes; Rojas, Denise Bertin; Moraes, Tarsila Barros; Dutra-Filho, Carlos Severo; Wannmacher, Clóvis Milton Duval.

Affiliation

Berti SL; Departamento de Bioquímica, Programa de Pós-Graduação em Ciências Biológicas: Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, 90035-003 Porto Alegre, RS, Brazil.

Metab Brain Dis ; 27(1): 79-89, 2012 Mar.

Article in En | MEDLINE | ID: mdl-22101931

Subject(s)

Creatine/administration & dosage; Hippocampus/drug effects; Oxidative Stress/drug effects; Phenylalanine/adverse effects; Phenylketonurias/metabolism; Pyruvic Acid/administration & dosage; Animals; Antioxidants/pharmacology; Energy Metabolism/drug effects; Exploratory Behavior/drug effects; Habituation, Psychophysiologic/drug effects; Hippocampus/metabolism; Humans; Lipid Peroxidation/drug effects; Male; Phenylalanine/administration & dosage; Phenylketonurias/pathology; Rats; Rats, Wistar

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenylalanine / Phenylketonurias / Oxidative Stress / Pyruvic Acid / Creatine / Hippocampus Limits: Animals / Humans / Male Language: En Journal: Metab Brain Dis Journal subject: CEREBRO / METABOLISMO Year: 2012 Type: Article Affiliation country: Brazil

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