Phospholipase D2 (PLD2) is a guanine nucleotide exchange factor (GEF) for the GTPase Rac2.

Mahankali, Madhu; Peng, Hong-Juan; Henkels, Karen M; Dinauer, Mary C; Gomez-Cambronero, Julian

Mahankali, Madhu; Peng, Hong-Juan; Henkels, Karen M; Dinauer, Mary C; Gomez-Cambronero, Julian.

Affiliation

Mahankali M; Department of Biochemistry and Molecular Biology, Wright State University School of Medicine, Dayton, OH 45435, USA.

Proc Natl Acad Sci U S A ; 108(49): 19617-22, 2011 Dec 06.

Article in En | MEDLINE | ID: mdl-22106281

Subject(s)

Guanine Nucleotide Exchange Factors/metabolism; Phospholipase D/metabolism; rac GTP-Binding Proteins/metabolism; Animals; Binding Sites/genetics; COS Cells; Cell Line; Cells, Cultured; Chlorocebus aethiops; Guanine Nucleotide Exchange Factors/genetics; Guanosine Diphosphate/metabolism; Guanosine Triphosphate/metabolism; Immunoblotting; Microscopy, Fluorescence; Mutation; Phosphatidic Acids/pharmacology; Phospholipase D/genetics; Protein Binding/drug effects; RNA Interference; Recombinant Proteins/metabolism; Spodoptera; rac GTP-Binding Proteins/genetics; RAC2 GTP-Binding Protein

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phospholipase D / Rac GTP-Binding Proteins / Guanine Nucleotide Exchange Factors Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2011 Type: Article Affiliation country: United States

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