Glucocorticoid-induced tumor necrosis factor receptor family-related protein regulates CD4(+)T cell-mediated colitis in mice.

Liao, Gongxian; Detre, Cynthia; Berger, Scott B; Engel, Pablo; de Waal Malefyt, Rene; Herzog, Roland W; Bhan, Atul K; Terhorst, Cox

Liao, Gongxian; Detre, Cynthia; Berger, Scott B; Engel, Pablo; de Waal Malefyt, Rene; Herzog, Roland W; Bhan, Atul K; Terhorst, Cox.

Affiliation

Liao G; Division of Immunology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA. gliao@bidmc.harvard.edu

Gastroenterology ; 142(3): 582-591.e8, 2012 Mar.

Article in En | MEDLINE | ID: mdl-22155173

Subject(s)

CD4-Positive T-Lymphocytes/immunology; Colitis/immunology; Colon/immunology; Glucocorticoid-Induced TNFR-Related Protein/metabolism; T-Lymphocyte Subsets/immunology; Animals; Antigens, CD/metabolism; CD4-Positive T-Lymphocytes/metabolism; CD4-Positive T-Lymphocytes/transplantation; Cell Proliferation; Cells, Cultured; Chronic Disease; Colitis/genetics; Colitis/metabolism; Colitis/pathology; Colon/metabolism; Colon/pathology; Cytokines/metabolism; Dendritic Cells/immunology; Disease Models, Animal; Glucocorticoid-Induced TNFR-Related Protein/deficiency; Glucocorticoid-Induced TNFR-Related Protein/genetics; Homeodomain Proteins/genetics; Homeodomain Proteins/metabolism; Inflammation Mediators/metabolism; Integrin alpha Chains/metabolism; Intestinal Mucosa/immunology; Ligands; Lymph Nodes/immunology; Lymphocyte Transfusion; Macrophages/immunology; Mice; Mice, Inbred C57BL; Mice, Knockout; Severity of Illness Index; T-Lymphocyte Subsets/metabolism; T-Lymphocyte Subsets/transplantation; T-Lymphocytes, Regulatory/immunology; Th1 Cells/immunology; Th17 Cells/immunology; Time Factors

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: CD4-Positive T-Lymphocytes / T-Lymphocyte Subsets / Colitis / Colon / Glucocorticoid-Induced TNFR-Related Protein Language: En Journal: Gastroenterology Year: 2012 Type: Article Affiliation country: United States

Fulltext

XML

PubMed Links

Search on Google