Characterization of DNA methyltransferase specificities using single-molecule, real-time DNA sequencing.

Clark, Tyson A; Murray, Iain A; Morgan, Richard D; Kislyuk, Andrey O; Spittle, Kristi E; Boitano, Matthew; Fomenkov, Alexey; Roberts, Richard J; Korlach, Jonas

Clark, Tyson A; Murray, Iain A; Morgan, Richard D; Kislyuk, Andrey O; Spittle, Kristi E; Boitano, Matthew; Fomenkov, Alexey; Roberts, Richard J; Korlach, Jonas.

Affiliation

Clark TA; Pacific Biosciences, 1380 Willow Road, Menlo Park, CA 94025, USA.

Nucleic Acids Res ; 40(4): e29, 2012 Feb.

Article in En | MEDLINE | ID: mdl-22156058

Subject(s)

DNA Methylation; DNA Modification Methylases/metabolism; Sequence Analysis, DNA; Bacteria/enzymology; Base Sequence; DNA (Cytosine-5-)-Methyltransferases/metabolism; Molecular Sequence Data; Plasmids/chemistry; Site-Specific DNA-Methyltransferase (Adenine-Specific)/metabolism; Site-Specific DNA-Methyltransferase (Cytosine-N4-Specific)/metabolism; Substrate Specificity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Modification Methylases / Sequence Analysis, DNA / DNA Methylation Language: En Journal: Nucleic Acids Res Year: 2012 Type: Article Affiliation country: United States

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