Activation of a Tip60/E2F1/ERCC1 network in human lung adenocarcinoma cells exposed to cisplatin.

Van Den Broeck, Arnaud; Nissou, Damien; Brambilla, Elisabeth; Eymin, Beatrice; Gazzeri, Sylvie

Van Den Broeck, Arnaud; Nissou, Damien; Brambilla, Elisabeth; Eymin, Beatrice; Gazzeri, Sylvie.

Affiliation

Van Den Broeck A; Equipe Bases Moléculaires de la Progression des Cancers du Poumon, Centre de Recherche INSERM U823, Institut Albert Bonniot BP170, 38042 Grenoble Cedex 09, France.

Carcinogenesis ; 33(2): 320-5, 2012 Feb.

Article in En | MEDLINE | ID: mdl-22159227

Subject(s)

Adenocarcinoma/drug therapy; Adenocarcinoma/metabolism; Antineoplastic Agents/pharmacology; Cisplatin/pharmacology; DNA-Binding Proteins/metabolism; E2F1 Transcription Factor/metabolism; Endonucleases/metabolism; Histone Acetyltransferases/metabolism; Lung Neoplasms/drug therapy; Lung Neoplasms/metabolism; Acetylation/drug effects; Adenocarcinoma/genetics; Adenocarcinoma of Lung; Apoptosis/drug effects; Binding Sites/drug effects; Cell Line, Tumor; DNA Damage; DNA Repair; E1A-Associated p300 Protein/metabolism; Humans; Lung Neoplasms/genetics; Lysine/metabolism; Lysine Acetyltransferase 5; Protein Interaction Domains and Motifs/drug effects; Up-Regulation/drug effects; p300-CBP Transcription Factors/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adenocarcinoma / Cisplatin / DNA-Binding Proteins / Endonucleases / Histone Acetyltransferases / E2F1 Transcription Factor / Lung Neoplasms / Antineoplastic Agents Limits: Humans Language: En Journal: Carcinogenesis Year: 2012 Type: Article Affiliation country: France

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