Verbascoside is not genotoxic in the ST and HB crosses of the Drosophila wing spot test, and its constituent, caffeic acid, decreases the spontaneous mutation rate in the ST cross.

Santos-Cruz, Luis Felipe; Ávila-Acevedo, José Guillermo; Ortega-Capitaine, Diego; Ojeda-Duplancher, Jesús Clemente; Perdigón-Moya, Juana Laura; Hernández-Portilla, Luis Barbo; López-Dionicio, Héctor; Durán-Díaz, Angel; Dueñas-García, Irma Elena; Castañeda-Partida, Laura; García-Bores, Ana María; Heres-Pulido, María Eugenia

Santos-Cruz, Luis Felipe; Ávila-Acevedo, José Guillermo; Ortega-Capitaine, Diego; Ojeda-Duplancher, Jesús Clemente; Perdigón-Moya, Juana Laura; Hernández-Portilla, Luis Barbo; López-Dionicio, Héctor; Durán-Díaz, Angel; Dueñas-García, Irma Elena; Castañeda-Partida, Laura; García-Bores, Ana María; Heres-Pulido, María Eugenia.

Affiliation

Santos-Cruz LF; Genetic Toxicology, Biology, UNAM FES Iztacala, Av. Los Barrios No. 1, Los Reyes Iztacala, CP. 54090, Tlalnepantla, Estado de México, Mexico.

Food Chem Toxicol ; 50(3-4): 1082-90, 2012 Mar.

Article in En | MEDLINE | ID: mdl-22197714

Subject(s)

Caffeic Acids/pharmacology; Glucosides/pharmacology; Mutation; Phenols/pharmacology; Wings, Animal/drug effects; Animals; Anti-Inflammatory Agents/chemistry; Anti-Inflammatory Agents/pharmacokinetics; Anti-Inflammatory Agents/pharmacology; Antioxidants/chemistry; Antioxidants/pharmacokinetics; Antioxidants/pharmacology; Biotransformation; Chromatography, High Pressure Liquid; Drosophila; Glucosides/chemistry; Glucosides/pharmacokinetics; Mutagenicity Tests; Phenols/chemistry; Phenols/pharmacokinetics; Ultraviolet Rays

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenols / Wings, Animal / Caffeic Acids / Glucosides / Mutation Limits: Animals Language: En Journal: Food Chem Toxicol Year: 2012 Type: Article Affiliation country: Mexico

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