Barrett's metaplasia glands are clonal, contain multiple stem cells and share a common squamous progenitor.

Nicholson, Anna M; Graham, Trevor A; Simpson, Ashley; Humphries, Adam; Burch, Nicola; Rodriguez-Justo, Manuel; Novelli, Marco; Harrison, Rebecca; Wright, Nicholas A; McDonald, Stuart A C; Jankowski, Janusz A

Nicholson, Anna M; Graham, Trevor A; Simpson, Ashley; Humphries, Adam; Burch, Nicola; Rodriguez-Justo, Manuel; Novelli, Marco; Harrison, Rebecca; Wright, Nicholas A; McDonald, Stuart A C; Jankowski, Janusz A.

Affiliation

Nicholson AM; Department of Oncology, University of Oxford, Oxford, UK.

Gut ; 61(10): 1380-9, 2012 Oct.

Article in En | MEDLINE | ID: mdl-22200839

Subject(s)

Barrett Esophagus/pathology; Cell Transformation, Neoplastic/pathology; Neoplastic Stem Cells/pathology; Aged; Barrett Esophagus/genetics; Barrett Esophagus/metabolism; Biomarkers, Tumor/genetics; Biomarkers, Tumor/metabolism; Cell Transformation, Neoplastic/genetics; Cell Transformation, Neoplastic/metabolism; DNA, Mitochondrial; Electron Transport Complex IV/genetics; Electron Transport Complex IV/metabolism; Epithelial Cells/metabolism; Epithelial Cells/pathology; Epithelium/metabolism; Epithelium/pathology; Fluorescent Antibody Technique; Genetic Markers; Humans; Metaplasia/genetics; Metaplasia/metabolism; Metaplasia/pathology; Middle Aged; Mutation; Neoplastic Stem Cells/metabolism; Sequence Analysis, DNA

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplastic Stem Cells / Barrett Esophagus / Cell Transformation, Neoplastic Limits: Aged / Humans / Middle aged Language: En Journal: Gut Year: 2012 Type: Article Affiliation country: United kingdom

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