ETS-related gene (ERG) controls endothelial cell permeability via transcriptional regulation of the claudin 5 (CLDN5) gene.

Yuan, Lei; Le Bras, Alexandra; Sacharidou, Anastasia; Itagaki, Kiyoshi; Zhan, Yumei; Kondo, Maiko; Carman, Christopher V; Davis, George E; Aird, William C; Oettgen, Peter

Yuan, Lei; Le Bras, Alexandra; Sacharidou, Anastasia; Itagaki, Kiyoshi; Zhan, Yumei; Kondo, Maiko; Carman, Christopher V; Davis, George E; Aird, William C; Oettgen, Peter.

Affiliation

Yuan L; Division of Cardiology, Harvard Medical School, Boston, Massachusetts 02215, USA.

J Biol Chem ; 287(9): 6582-91, 2012 Feb 24.

Article in En | MEDLINE | ID: mdl-22235125

Subject(s)

Capillary Permeability/physiology; Claudins/genetics; Endothelial Cells/metabolism; Trans-Activators/metabolism; Transcriptional Activation/physiology; Adenoviridae/genetics; Capillary Permeability/drug effects; Claudin-5; Coronary Vessels/cytology; Cytoskeleton/physiology; Gene Knockdown Techniques; Human Umbilical Vein Endothelial Cells; Humans; Intercellular Junctions/physiology; Microvessels/cytology; Mutagenesis, Site-Directed; Pulmonary Artery/cytology; Trans-Activators/genetics; Transcriptional Regulator ERG; Tumor Necrosis Factor-alpha/pharmacology

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Capillary Permeability / Transcriptional Activation / Trans-Activators / Endothelial Cells / Claudins Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Biol Chem Year: 2012 Type: Article Affiliation country: United States

Fulltext

XML

PubMed Links

Search on Google