Expression profiles of human interferon-alpha and interferon-lambda subtypes are ligand- and cell-dependent.

Hillyer, Philippa; Mane, Viraj P; Schramm, Lynnsie M; Puig, Montserrat; Verthelyi, Daniela; Chen, Aaron; Zhao, Zeng; Navarro, Maria B; Kirschman, Kevin D; Bykadi, Srikant; Jubin, Ronald G; Rabin, Ronald L

Hillyer, Philippa; Mane, Viraj P; Schramm, Lynnsie M; Puig, Montserrat; Verthelyi, Daniela; Chen, Aaron; Zhao, Zeng; Navarro, Maria B; Kirschman, Kevin D; Bykadi, Srikant; Jubin, Ronald G; Rabin, Ronald L.

Affiliation

Hillyer P; Center for Biologics Evaluation and Research, US Food and Drug Administration, Bethesda, MD 20892-4555, USA.

Immunol Cell Biol ; 90(8): 774-83, 2012 Sep.

Article in En | MEDLINE | ID: mdl-22249201

Subject(s)

Gene Expression Profiling; Interferon-alpha/genetics; Interleukins/genetics; Animals; DNA Probes/metabolism; Dendritic Cells/drug effects; Dendritic Cells/metabolism; Gene Expression Regulation/drug effects; Humans; Interferon-alpha/metabolism; Interferons; Interleukins/metabolism; Ligands; Lipopolysaccharides/pharmacology; Macrophages/drug effects; Macrophages/metabolism; Mice; Myeloid Cells/drug effects; Myeloid Cells/metabolism; Oligodeoxyribonucleotides/pharmacology; Organ Specificity/drug effects; Organ Specificity/genetics; Poly I-C/pharmacology; RNA, Messenger/genetics; RNA, Messenger/metabolism; Reproducibility of Results; Toll-Like Receptors/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interleukins / Interferon-alpha / Gene Expression Profiling Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Immunol Cell Biol Journal subject: ALERGIA E IMUNOLOGIA Year: 2012 Type: Article Affiliation country: United States

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