Enhancer decommissioning by LSD1 during embryonic stem cell differentiation.

Whyte, Warren A; Bilodeau, Steve; Orlando, David A; Hoke, Heather A; Frampton, Garrett M; Foster, Charles T; Cowley, Shaun M; Young, Richard A

Whyte, Warren A; Bilodeau, Steve; Orlando, David A; Hoke, Heather A; Frampton, Garrett M; Foster, Charles T; Cowley, Shaun M; Young, Richard A.

Affiliation

Whyte WA; Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA.

Nature ; 482(7384): 221-5, 2012 Feb 01.

Article in En | MEDLINE | ID: mdl-22297846

Subject(s)

Cell Differentiation/genetics; Embryonic Stem Cells/cytology; Embryonic Stem Cells/metabolism; Enhancer Elements, Genetic/genetics; Gene Silencing; Oxidoreductases, N-Demethylating/metabolism; Animals; Fibroblasts; Histone Demethylases; Mi-2 Nucleosome Remodeling and Deacetylase Complex/metabolism; Mice; Oxidoreductases, N-Demethylating/antagonists & inhibitors; Promoter Regions, Genetic/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxidoreductases, N-Demethylating / Cell Differentiation / Enhancer Elements, Genetic / Gene Silencing / Embryonic Stem Cells Limits: Animals Language: En Journal: Nature Year: 2012 Type: Article Affiliation country: United States

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