Deciphering the role of the ERCC2 gene polymorphism on anticancer drug sensitivity.

Moisan, François; Laroche-Clary, Audrey; Auzanneau, Céline; Ricard, Nicolas; Pourquier, Philippe; Robert, Jacques; Le Morvan, Valérie

Moisan, François; Laroche-Clary, Audrey; Auzanneau, Céline; Ricard, Nicolas; Pourquier, Philippe; Robert, Jacques; Le Morvan, Valérie.

Affiliation

Moisan F; Department of Pharmacology, INSERM Unit 916, Institut Bergonié, 229 cours de l'Argonne, 33076 Bordeaux, France.

Carcinogenesis ; 33(5): 962-8, 2012 May.

Article in En | MEDLINE | ID: mdl-22345163

Subject(s)

Antineoplastic Agents/pharmacology; Drug Resistance, Neoplasm/genetics; Xeroderma Pigmentosum Group D Protein/genetics; Adult; Cell Division/genetics; Cell Line, Tumor; Cisplatin/pharmacology; Cyclin-Dependent Kinases/genetics; DNA Repair; DNA-Binding Proteins/genetics; Drug Screening Assays, Antitumor/methods; Female; Fibroblasts/metabolism; G2 Phase/genetics; Gene Expression; Histones/metabolism; Humans; Paclitaxel/pharmacology; Phosphorylation; Polymorphism, Genetic; RNA, Messenger/genetics; Taxoids/pharmacology; Transcription Factor TFIIH/genetics; Young Adult; Cyclin-Dependent Kinase-Activating Kinase

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Resistance, Neoplasm / Xeroderma Pigmentosum Group D Protein / Antineoplastic Agents Type of study: Diagnostic_studies / Qualitative_research Limits: Adult / Female / Humans Language: En Journal: Carcinogenesis Year: 2012 Type: Article Affiliation country: France

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