Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repair.

Polo, Sophie E; Blackford, Andrew N; Chapman, J Ross; Baskcomb, Linda; Gravel, Serge; Rusch, Andre; Thomas, Anoushka; Blundred, Rachel; Smith, Philippa; Kzhyshkowska, Julia; Dobner, Thomas; Taylor, A Malcolm R; Turnell, Andrew S; Stewart, Grant S; Grand, Roger J; Jackson, Stephen P

Polo, Sophie E; Blackford, Andrew N; Chapman, J Ross; Baskcomb, Linda; Gravel, Serge; Rusch, Andre; Thomas, Anoushka; Blundred, Rachel; Smith, Philippa; Kzhyshkowska, Julia; Dobner, Thomas; Taylor, A Malcolm R; Turnell, Andrew S; Stewart, Grant S; Grand, Roger J; Jackson, Stephen P.

Affiliation

Polo SE; The Gurdon Institute, Department of Biochemistry, University of Cambridge, UK.

Mol Cell ; 45(4): 505-16, 2012 Feb 24.

Article in En | MEDLINE | ID: mdl-22365830

Subject(s)

DNA Breaks, Double-Stranded; DNA End-Joining Repair; Heterogeneous-Nuclear Ribonucleoproteins/physiology; Nuclear Proteins/physiology; Transcription Factors/physiology; Acid Anhydride Hydrolases; Carrier Proteins/genetics; Carrier Proteins/metabolism; Carrier Proteins/physiology; Cell Cycle Proteins/metabolism; DNA Repair Enzymes/metabolism; DNA-Binding Proteins/metabolism; Endodeoxyribonucleases; Heterogeneous-Nuclear Ribonucleoproteins/genetics; Heterogeneous-Nuclear Ribonucleoproteins/metabolism; Humans; MRE11 Homologue Protein; Nuclear Proteins/genetics; Nuclear Proteins/metabolism; Signal Transduction; Transcription Factors/genetics; Transcription Factors/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Nuclear Proteins / Heterogeneous-Nuclear Ribonucleoproteins / DNA Breaks, Double-Stranded / DNA End-Joining Repair Type of study: Prognostic_studies Limits: Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2012 Type: Article Affiliation country: United kingdom

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