c-Myb interacts with the glucocorticoid receptor and regulates its level in pre-B-acute lymphoblastic leukemia cells.

Sarvaiya, Purvaba J; Schwartz, Jason R; Geng, Chuan-dong; Vedeckis, Wayne V

Sarvaiya, Purvaba J; Schwartz, Jason R; Geng, Chuan-dong; Vedeckis, Wayne V.

Affiliation

Sarvaiya PJ; Department of Biochemistry and Molecular Biology, Stanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, LA 70112, United States.

Mol Cell Endocrinol ; 361(1-2): 124-32, 2012 Sep 25.

Article in En | MEDLINE | ID: mdl-22516378

Subject(s)

Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/metabolism; Proto-Oncogene Proteins c-myb/metabolism; Receptors, Glucocorticoid/metabolism; Animals; Apoptosis/drug effects; Cell Line, Tumor; Dexamethasone/pharmacology; Doxycycline/pharmacology; Gene Expression Regulation, Leukemic/drug effects; Gene Knockdown Techniques; Humans; Mice; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/genetics; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/pathology; Promoter Regions, Genetic/genetics; Protein Binding/drug effects; RNA, Messenger/genetics; RNA, Messenger/metabolism; Receptors, Glucocorticoid/genetics; Steroids/pharmacology; Up-Regulation/drug effects; Up-Regulation/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Receptors, Glucocorticoid / Proto-Oncogene Proteins c-myb Limits: Animals / Humans Language: En Journal: Mol Cell Endocrinol Year: 2012 Type: Article Affiliation country: United States

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