Fanconi anemia and vaginal squamous cell carcinoma.
Rare Tumors
; 4(1): e4, 2012 Jan 02.
Article
in En
| MEDLINE
| ID: mdl-22532920
ABSTRACT
Fanconi Anemia (FA) is an autosomal recessive disease characterized by chromosome instability, cellular hypersensitivity to DNA cross-linking agents, and increased predisposition to malignancies. We describe here a 28 year-old female with FA and vaginal squamous cell carcinoma treated by radiation therapy alone. The patient developed arm phlebitis, pulmonary fungal infection, and severe rectal bleeding, followed by hypocalcaemia, hypokalemia, vaginal bacterial and fungal infection, with subsequent leg and arm phlebitis, perineal abscess, and sepsis. The patient died 12 weeks later.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Rare Tumors
Year:
2012
Type:
Article