Stromal factors SDF1&#945;, sFRP1, and VEGFD induce dopaminergic neuron differentiation of human pluripotent stem cells.

Schwartz, Catherine M; Tavakoli, Tahereh; Jamias, Charmaine; Park, Sung-Soo; Maudsley, Stuart; Martin, Bronwen; Phillips, Terry M; Yao, Pamela J; Itoh, Katsuhiko; Ma, Wu; Rao, Mahendra S; Arenas, Ernest; Mattson, Mark P

Stromal factors SDF1α, sFRP1, and VEGFD induce dopaminergic neuron differentiation of human pluripotent stem cells.

Schwartz, Catherine M; Tavakoli, Tahereh; Jamias, Charmaine; Park, Sung-Soo; Maudsley, Stuart; Martin, Bronwen; Phillips, Terry M; Yao, Pamela J; Itoh, Katsuhiko; Ma, Wu; Rao, Mahendra S; Arenas, Ernest; Mattson, Mark P.

Affiliation

Schwartz CM; National Institute on Aging Intramural Research Program, National Institutes of Health, Laboratory of Neurosciences, Baltimore, MD 21224, USA.

J Neurosci Res ; 90(7): 1367-81, 2012 Jul.

Article in En | MEDLINE | ID: mdl-22535492

Subject(s)

Dopaminergic Neurons/cytology; Nerve Growth Factors/biosynthesis; Neural Stem Cells/drug effects; Neurogenesis/physiology; Pluripotent Stem Cells/drug effects; Animals; Biomarkers/metabolism; Cell Culture Techniques; Cell Line; Cell Line, Tumor; Chemokine CXCL12/biosynthesis; Chemokine CXCL12/physiology; Dopaminergic Neurons/metabolism; Embryonal Carcinoma Stem Cells/cytology; Embryonal Carcinoma Stem Cells/drug effects; Embryonal Carcinoma Stem Cells/metabolism; Humans; Intercellular Signaling Peptides and Proteins/pharmacology; Intercellular Signaling Peptides and Proteins/physiology; Membrane Proteins/pharmacology; Membrane Proteins/physiology; Mice; Neural Stem Cells/cytology; Neural Stem Cells/metabolism; Pluripotent Stem Cells/cytology; Pluripotent Stem Cells/metabolism; Stromal Cells/metabolism; Tubulin/biosynthesis; Tyrosine 3-Monooxygenase/biosynthesis; Vascular Endothelial Growth Factor D/biosynthesis; Vascular Endothelial Growth Factor D/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pluripotent Stem Cells / Neurogenesis / Neural Stem Cells / Dopaminergic Neurons / Nerve Growth Factors Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Neurosci Res Year: 2012 Type: Article Affiliation country: United States

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