NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells.

Eisenbarth, Stephanie C; Williams, Adam; Colegio, Oscar R; Meng, Hailong; Strowig, Till; Rongvaux, Anthony; Henao-Mejia, Jorge; Thaiss, Christoph A; Joly, Sophie; Gonzalez, David G; Xu, Lan; Zenewicz, Lauren A; Haberman, Ann M; Elinav, Eran; Kleinstein, Steven H; Sutterwala, Fayyaz S; Flavell, Richard A

Eisenbarth, Stephanie C; Williams, Adam; Colegio, Oscar R; Meng, Hailong; Strowig, Till; Rongvaux, Anthony; Henao-Mejia, Jorge; Thaiss, Christoph A; Joly, Sophie; Gonzalez, David G; Xu, Lan; Zenewicz, Lauren A; Haberman, Ann M; Elinav, Eran; Kleinstein, Steven H; Sutterwala, Fayyaz S; Flavell, Richard A.

Affiliation

Eisenbarth SC; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA.

Nature ; 484(7395): 510-3, 2012 Apr 25.

Article in En | MEDLINE | ID: mdl-22538615

Subject(s)

Adaptive Immunity/immunology; Apoptosis Regulatory Proteins/metabolism; Dendritic Cells/immunology; Adaptor Proteins, Signal Transducing; Adjuvants, Immunologic; Animals; Antigens/immunology; Apoptosis Regulatory Proteins/deficiency; Apoptosis Regulatory Proteins/genetics; Apoptosis Regulatory Proteins/immunology; Caspase 1; Cell Movement; Chemokines/immunology; Dendritic Cells/cytology; Dendritic Cells/metabolism; Gene Deletion; Inflammasomes; Ligands; Lymph Nodes/immunology; Mice; Mice, Inbred BALB C; T-Lymphocytes/immunology; T-Lymphocytes, Helper-Inducer/immunology; Vaccines/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dendritic Cells / Apoptosis Regulatory Proteins / Adaptive Immunity Limits: Animals Language: En Journal: Nature Year: 2012 Type: Article Affiliation country: United States

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