Gene expression signatures modulated by epidermal growth factor receptor activation and their relationship to cetuximab resistance in head and neck squamous cell carcinoma.

Fertig, Elana J; Ren, Qing; Cheng, Haixia; Hatakeyama, Hiromitsu; Dicker, Adam P; Rodeck, Ulrich; Considine, Michael; Ochs, Michael F; Chung, Christine H

Fertig, Elana J; Ren, Qing; Cheng, Haixia; Hatakeyama, Hiromitsu; Dicker, Adam P; Rodeck, Ulrich; Considine, Michael; Ochs, Michael F; Chung, Christine H.

Affiliation

Fertig EJ; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, School of Medicine, Johns Hopkins University, Baltimore, MD, USA. ejfertig@jhmi.edu

BMC Genomics ; 13: 160, 2012 May 01.

Article in En | MEDLINE | ID: mdl-22549044

Subject(s)

Antibodies, Monoclonal/pharmacology; Carcinoma, Squamous Cell/metabolism; ErbB Receptors/metabolism; Head and Neck Neoplasms/metabolism; Algorithms; Antibodies, Monoclonal, Humanized; Cell Line, Tumor; Cetuximab; Drug Resistance, Neoplasm/genetics; ErbB Receptors/genetics; Humans; Keratinocytes/cytology; Keratinocytes/drug effects; Keratinocytes/metabolism; Protein Binding/drug effects; Signal Transduction/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Squamous Cell / ErbB Receptors / Head and Neck Neoplasms / Antibodies, Monoclonal Type of study: Prognostic_studies Limits: Humans Language: En Journal: BMC Genomics Journal subject: GENETICA Year: 2012 Type: Article Affiliation country: United States

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