Regeneration of pancreatic non-ß endocrine cells in adult mice following a single diabetes-inducing dose of streptozotocin.

Zhang, Yanqing; Zhang, Yuan; Bone, Robert N; Cui, Wanxing; Peng, Ji-Bin; Siegal, Gene P; Wang, Hongjun; Wu, Hongju

Zhang, Yanqing; Zhang, Yuan; Bone, Robert N; Cui, Wanxing; Peng, Ji-Bin; Siegal, Gene P; Wang, Hongjun; Wu, Hongju.

Affiliation

Zhang Y; Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, Alabama, USA.

PLoS One ; 7(5): e36675, 2012.

Article in En | MEDLINE | ID: mdl-22586489

Subject(s)

Cell Proliferation; Glucagon-Secreting Cells; Islets of Langerhans/cytology; Somatostatin-Secreting Cells; Streptozocin/pharmacology; Animals; Cell Count; Cell Proliferation/drug effects; Diabetes Mellitus, Experimental/metabolism; Diabetes Mellitus, Experimental/pathology; Disease Models, Animal; Dose-Response Relationship, Drug; Glucagon/genetics; Glucagon/metabolism; Glucagon-Secreting Cells/cytology; Glucagon-Secreting Cells/drug effects; Glucagon-Secreting Cells/metabolism; Homeodomain Proteins/genetics; Insulin/genetics; Insulin/metabolism; Insulin-Secreting Cells/drug effects; Islets of Langerhans/metabolism; Islets of Langerhans/pathology; Mice; Mice, Inbred C57BL; Regeneration/drug effects; Somatostatin/genetics; Somatostatin/metabolism; Somatostatin-Secreting Cells/cytology; Somatostatin-Secreting Cells/drug effects; Somatostatin-Secreting Cells/metabolism; Trans-Activators/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Islets of Langerhans / Streptozocin / Somatostatin-Secreting Cells / Cell Proliferation / Glucagon-Secreting Cells Type of study: Prognostic_studies Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2012 Type: Article Affiliation country: United States

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