Amyloid-ß protein modulates insulin signaling in presynaptic terminals.

Heras-Sandoval, David; Ferrera, Patricia; Arias, Clorinda

Heras-Sandoval, David; Ferrera, Patricia; Arias, Clorinda.

Affiliation

Heras-Sandoval D; Departamento de Medicina Genómica y Toxicología Ambiental, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico D.F., Mexico.

Neurochem Res ; 37(9): 1879-85, 2012 Sep.

Article in En | MEDLINE | ID: mdl-22638775

Subject(s)

Amyloid beta-Peptides/pharmacology; Insulin/physiology; Presynaptic Terminals/drug effects; Signal Transduction/drug effects; Animals; Blotting, Western; Cerebral Cortex/drug effects; Cerebral Cortex/metabolism; Hippocampus/drug effects; Hippocampus/metabolism; Hypoglycemic Agents/pharmacology; In Vitro Techniques; Insulin/pharmacology; Insulin Receptor Substrate Proteins/metabolism; Insulin Resistance/physiology; Male; Mitochondria/drug effects; Mitochondria/metabolism; Oncogene Protein v-akt/physiology; Oxidation-Reduction; Phosphatidylinositol 3-Kinases/metabolism; Rats; Receptor, Insulin/physiology; Synapses/drug effects; Synapses/pathology; Synaptosomes/drug effects; Synaptosomes/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Amyloid beta-Peptides / Presynaptic Terminals / Insulin Limits: Animals Language: En Journal: Neurochem Res Year: 2012 Type: Article Affiliation country: Mexico

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