Adenosine receptor A2b on hematopoietic cells mediates LPS-induced migration of PMNs into the lung interstitium.

Konrad, Franziska M; Witte, Esther; Vollmer, Irene; Stark, Stefanie; Reutershan, Jörg

Konrad, Franziska M; Witte, Esther; Vollmer, Irene; Stark, Stefanie; Reutershan, Jörg.

Affiliation

Konrad FM; Dept. of Anesthesiology and Intensive Care Medicine, Univ. of Tübingen, Tübingen, Germany.

Am J Physiol Lung Cell Mol Physiol ; 303(5): L425-38, 2012 Sep.

Article in En | MEDLINE | ID: mdl-22707616

Subject(s)

Bone Marrow Cells/metabolism; Lipopolysaccharides/pharmacology; Lung/pathology; Neutrophils/physiology; Pneumonia/metabolism; Receptor, Adenosine A2B/metabolism; Transendothelial and Transepithelial Migration; Acute Lung Injury/immunology; Acute Lung Injury/metabolism; Acute Lung Injury/pathology; Adenosine A2 Receptor Agonists/pharmacology; Aminopyridines/pharmacology; Animals; Bone Marrow Transplantation; Bronchoalveolar Lavage Fluid; Capillary Permeability; Cell Count; Cells, Cultured; Chemokines/metabolism; Cytoskeleton/metabolism; Gene Expression; Gene Expression Regulation; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils/drug effects; Pneumonia/immunology; Pneumonia/pathology; Receptor, Adenosine A2B/genetics; Receptor, Adenosine A2B/physiology; Respiratory Burst

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pneumonia / Bone Marrow Cells / Lipopolysaccharides / Receptor, Adenosine A2B / Transendothelial and Transepithelial Migration / Lung / Neutrophils Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Am J Physiol Lung Cell Mol Physiol Journal subject: BIOLOGIA MOLECULAR / FISIOLOGIA Year: 2012 Type: Article Affiliation country: Germany

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