A zebrafish model of intrahepatic cholangiocarcinoma by dual expression of hepatitis B virus X and hepatitis C virus core protein in liver.

Liu, Wangta; Chen, Jim-Ray; Hsu, Chih-Hao; Li, Yen-Hsing; Chen, Yi-Meng; Lin, Chien-Yuan; Huang, Shin-Jie; Chang, Zen-Kuei; Chen, Yen-Chun; Lin, Chi-Hsueh; Gong, Hong-Yi; Lin, Ching-Chun; Kawakami, Koichi; Wu, Jen-Leih

Liu, Wangta; Chen, Jim-Ray; Hsu, Chih-Hao; Li, Yen-Hsing; Chen, Yi-Meng; Lin, Chien-Yuan; Huang, Shin-Jie; Chang, Zen-Kuei; Chen, Yen-Chun; Lin, Chi-Hsueh; Gong, Hong-Yi; Lin, Ching-Chun; Kawakami, Koichi; Wu, Jen-Leih.

Affiliation

Liu W; Institute of Cellular and Organismic Biology, Academia Sinica, Taipei, Taiwan.

Hepatology ; 56(6): 2268-76, 2012 Dec.

Article in En | MEDLINE | ID: mdl-22729936

Subject(s)

Bile Duct Neoplasms/genetics; Bile Ducts, Intrahepatic; Cholangiocarcinoma/genetics; Disease Models, Animal; Hepacivirus; Trans-Activators/genetics; Viral Core Proteins/genetics; Zebrafish; Animals; Animals, Genetically Modified; Anti-Bacterial Agents/pharmacology; Bile Duct Neoplasms/pathology; Cholangiocarcinoma/pathology; Connective Tissue Growth Factor/genetics; Cyclin D1/genetics; Doxycycline/pharmacology; Gene Expression/drug effects; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3/genetics; Smad2 Protein/genetics; Smad3 Protein/genetics; Transforming Growth Factor beta1/genetics; Up-Regulation; Vascular Endothelial Growth Factor A/genetics; Viral Regulatory and Accessory Proteins; Zebrafish Proteins/genetics; p38 Mitogen-Activated Protein Kinases/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bile Duct Neoplasms / Bile Ducts, Intrahepatic / Zebrafish / Trans-Activators / Viral Core Proteins / Cholangiocarcinoma / Hepacivirus / Disease Models, Animal Type of study: Prognostic_studies Limits: Animals Language: En Journal: Hepatology Year: 2012 Type: Article Affiliation country: Taiwan

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