Genetics and pharmacogenomics in pulmonary arterial hypertension.
Heart Fail Clin
; 8(3): 319-30, 2012 Jul.
Article
in En
| MEDLINE
| ID: mdl-22748897
ABSTRACT
Pulmonary arterial hypertension (PAH) is an uncommon disease in the general population, but a disease with significant morbidity and mortality. The prevalence of heritable PAH (HPAH) remains unknown. The reason for incomplete penetrance of HPAH is not well understood. A patient's clinical response to disease-specific therapy is complex, involving the severity of the patient's disease, other comorbidities, appropriateness of the prescribed therapy, and patient compliance. Warfarin is often used as an adjuvant therapy in patients with PAH.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pharmacogenetics
/
Pulmonary Artery
/
Hypertension, Pulmonary
Type of study:
Etiology_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Humans
Country/Region as subject:
America do norte
Language:
En
Journal:
Heart Fail Clin
Year:
2012
Type:
Article
Affiliation country:
United States