STAT3 protein interacts with Class O Forkhead transcription factors in the cytoplasm and regulates nuclear/cytoplasmic localization of FoxO1 and FoxO3a proteins in CD4(+) T cells.

Oh, Hyun-Mee; Yu, Cheng-Rong; Dambuza, Ivy; Marrero, Bernadette; Egwuagu, Charles E

Oh, Hyun-Mee; Yu, Cheng-Rong; Dambuza, Ivy; Marrero, Bernadette; Egwuagu, Charles E.

Affiliation

Oh HM; Molecular Immunology Section, NEI, National Institutes of Health, Bethesda, MD 20892, USA.

J Biol Chem ; 287(36): 30436-43, 2012 Aug 31.

Article in En | MEDLINE | ID: mdl-22761423

Subject(s)

CD4-Positive T-Lymphocytes/metabolism; Cell Nucleus/metabolism; Cytoplasm/metabolism; Forkhead Transcription Factors/metabolism; STAT3 Transcription Factor/metabolism; 14-3-3 Proteins/genetics; 14-3-3 Proteins/immunology; 14-3-3 Proteins/metabolism; Active Transport, Cell Nucleus/immunology; Animals; CD4-Positive T-Lymphocytes/cytology; CD4-Positive T-Lymphocytes/immunology; Cell Nucleus/genetics; Cell Nucleus/immunology; Cyclin-Dependent Kinase Inhibitor p21/genetics; Cyclin-Dependent Kinase Inhibitor p21/immunology; Cyclin-Dependent Kinase Inhibitor p21/metabolism; Cyclin-Dependent Kinase Inhibitor p27/genetics; Cyclin-Dependent Kinase Inhibitor p27/immunology; Cyclin-Dependent Kinase Inhibitor p27/metabolism; Cytokines/genetics; Cytokines/immunology; Cytokines/metabolism; Cytoplasm/genetics; Cytoplasm/immunology; Forkhead Box Protein O1; Forkhead Box Protein O3; Forkhead Transcription Factors/genetics; Forkhead Transcription Factors/immunology; Gene Expression Regulation/immunology; Humans; Jurkat Cells; Lymphocyte Activation/physiology; Mice; Mice, Knockout; Receptors, Antigen, T-Cell/genetics; Receptors, Antigen, T-Cell/immunology; Receptors, Antigen, T-Cell/metabolism; STAT3 Transcription Factor/genetics; STAT3 Transcription Factor/immunology

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: CD4-Positive T-Lymphocytes / Cell Nucleus / Cytoplasm / STAT3 Transcription Factor / Forkhead Transcription Factors Language: En Journal: J Biol Chem Year: 2012 Type: Article Affiliation country: United States

Fulltext

XML

PubMed Links

Search on Google