Valsartan improves adipose tissue function in humans with impaired glucose metabolism: a randomized placebo-controlled double-blind trial.

Goossens, Gijs H; Moors, Chantalle C M; van der Zijl, Nynke J; Venteclef, Nicolas; Alili, Rohia; Jocken, Johan W E; Essers, Yvonne; Cleutjens, Jack P; Clément, Karine; Diamant, Michaela; Blaak, Ellen E

Goossens, Gijs H; Moors, Chantalle C M; van der Zijl, Nynke J; Venteclef, Nicolas; Alili, Rohia; Jocken, Johan W E; Essers, Yvonne; Cleutjens, Jack P; Clément, Karine; Diamant, Michaela; Blaak, Ellen E.

Affiliation

Goossens GH; Department of Human Biology, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Center, Maastricht, The Netherlands. G.Goossens@maastrichtuniversity.nl

PLoS One ; 7(6): e39930, 2012.

Article in En | MEDLINE | ID: mdl-22768174

Subject(s)

Adipose Tissue/drug effects; Adipose Tissue/physiopathology; Antihypertensive Agents/pharmacology; Glucose/metabolism; Tetrazoles/pharmacology; Valine/analogs & derivatives; Adipocytes/drug effects; Adipocytes/metabolism; Adipocytes/pathology; Adipose Tissue/blood supply; Adipose Tissue/pathology; Biomarkers/blood; Biomarkers/metabolism; Blood Pressure/drug effects; Capillaries/drug effects; Capillaries/pathology; Cell Hypoxia/drug effects; Cell Size/drug effects; Chemotactic Factors/pharmacology; Double-Blind Method; Fasting/blood; Female; Gene Expression Regulation/drug effects; Humans; Inflammation/metabolism; Inflammation/pathology; Insulin/pharmacology; Lipolysis/drug effects; Macrophages/drug effects; Macrophages/metabolism; Macrophages/pathology; Male; Middle Aged; Placebos; Postprandial Period; Valine/pharmacology; Valsartan

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tetrazoles / Valine / Adipose Tissue / Glucose / Antihypertensive Agents Type of study: Clinical_trials Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2012 Type: Article Affiliation country: Netherlands

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