Sumas Mountain chrysotile induces greater lung fibrosis in Fischer344 rats than Libby amphibole, El Dorado tremolite, and Ontario ferroactinolite.

Cyphert, Jaime M; Nyska, Abraham; Mahoney, Ron K; Schladweiler, Mette C; Kodavanti, Urmila P; Gavett, Stephen H

Cyphert, Jaime M; Nyska, Abraham; Mahoney, Ron K; Schladweiler, Mette C; Kodavanti, Urmila P; Gavett, Stephen H.

Affiliation

Cyphert JM; Curriculum in Toxicology, UNC School of Medicine, Chapel Hill, North Carolina 27599, USA.

Toxicol Sci ; 130(2): 405-15, 2012 Dec.

Article in En | MEDLINE | ID: mdl-22903825

Subject(s)

Asbestos, Amphibole/toxicity; Asbestos, Serpentine/toxicity; Lung/drug effects; Pulmonary Fibrosis/chemically induced; Animals; Asbestos, Amphibole/chemistry; Asbestos, Serpentine/chemistry; Bronchoalveolar Lavage Fluid/cytology; Bronchoalveolar Lavage Fluid/immunology; Dose-Response Relationship, Drug; Inflammation Mediators/metabolism; Inhalation Exposure; Lung/immunology; Lung/pathology; Particle Size; Pulmonary Fibrosis/immunology; Pulmonary Fibrosis/pathology; Rats; Rats, Inbred F344; Risk Assessment; Severity of Illness Index; Time Factors

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pulmonary Fibrosis / Asbestos, Serpentine / Asbestos, Amphibole / Lung Type of study: Etiology_studies / Risk_factors_studies Limits: Animals Language: En Journal: Toxicol Sci Journal subject: TOXICOLOGIA Year: 2012 Type: Article Affiliation country: United States

Fulltext

XML

PubMed Links

Search on Google