Influenza and malaria coinfection among young children in western Kenya, 2009-2011.
J Infect Dis
; 206(11): 1674-84, 2012 Dec 01.
Article
in En
| MEDLINE
| ID: mdl-22984118
ABSTRACT
BACKGROUND:
Although children <5 years old in sub-Saharan Africa are vulnerable to both malaria and influenza, little is known about coinfection.METHODS:
This retrospective, cross-sectional study in rural western Kenya examined outpatient visits and hospitalizations associated with febrile acute respiratory illness (ARI) during a 2-year period (July 2009-June 2011) in children <5 years old.RESULTS:
Across sites, 45% (149/331) of influenza-positive patients were coinfected with malaria, whereas only 6% (149/2408) of malaria-positive patients were coinfected with influenza. Depending on age, coinfection was present in 4%-8% of outpatient visits and 1%-3% of inpatient admissions for febrile ARI. Children with influenza were less likely than those without to have malaria (risk ratio [RR], 0.57-0.76 across sites and ages), and children with malaria were less likely than those without to have influenza (RR, 0.36-0.63). Among coinfected children aged 24-59 months, hospital length of stay was 2.7 and 2.8 days longer than influenza-only-infected children at the 2 sites, and 1.3 and 3.1 days longer than those with malaria only (all P < .01).CONCLUSIONS:
Coinfection with malaria and influenza was uncommon but associated with longer hospitalization than single infections among children 24-59 months of age.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Influenza, Human
/
Malaria
Type of study:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Newborn
Country/Region as subject:
Africa
Language:
En
Journal:
J Infect Dis
Year:
2012
Type:
Article
Affiliation country:
United States