Breast cancer risk-associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression.

Cowper-Sal lari, Richard; Zhang, Xiaoyang; Wright, Jason B; Bailey, Swneke D; Cole, Michael D; Eeckhoute, Jerome; Moore, Jason H; Lupien, Mathieu

Cowper-Sal lari, Richard; Zhang, Xiaoyang; Wright, Jason B; Bailey, Swneke D; Cole, Michael D; Eeckhoute, Jerome; Moore, Jason H; Lupien, Mathieu.

Affiliation

Cowper-Sal lari R; Department of Genetics, Norris Cotton Cancer Center, Dartmouth Medical School, Lebanon, New Hampshire, USA.

Nat Genet ; 44(11): 1191-8, 2012 Nov.

Article in En | MEDLINE | ID: mdl-23001124

Subject(s)

Breast Neoplasms/genetics; Chromatin/genetics; Hepatocyte Nuclear Factor 3-alpha/genetics; Receptors, Progesterone/genetics; Alleles; Apoptosis Regulatory Proteins; Estrogen Receptor alpha/genetics; Female; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Genome-Wide Association Study; High Mobility Group Proteins; Histone-Lysine N-Methyltransferase; Humans; Polymorphism, Single Nucleotide; Regulatory Sequences, Nucleic Acid; Risk Factors; Trans-Activators

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Chromatin / Receptors, Progesterone / Hepatocyte Nuclear Factor 3-alpha Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2012 Type: Article Affiliation country: United States

Fulltext

XML

PubMed Links

Search on Google