A fully humanized transgenic mouse model of Huntington disease.

Southwell, Amber L; Warby, Simon C; Carroll, Jeffrey B; Doty, Crystal N; Skotte, Niels H; Zhang, Weining; Villanueva, Erika B; Kovalik, Vlad; Xie, Yuanyun; Pouladi, Mahmoud A; Collins, Jennifer A; Yang, X William; Franciosi, Sonia; Hayden, Michael R

Southwell, Amber L; Warby, Simon C; Carroll, Jeffrey B; Doty, Crystal N; Skotte, Niels H; Zhang, Weining; Villanueva, Erika B; Kovalik, Vlad; Xie, Yuanyun; Pouladi, Mahmoud A; Collins, Jennifer A; Yang, X William; Franciosi, Sonia; Hayden, Michael R.

Affiliation

Southwell AL; Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, University of British Columbia, Vancouver, BC, Canada V5Z 4H4.

Hum Mol Genet ; 22(1): 18-34, 2013 Jan 01.

Article in En | MEDLINE | ID: mdl-23001568

Subject(s)

Disease Models, Animal; Huntington Disease/genetics; Animals; Gene Silencing; Humans; Huntington Disease/psychology; Mice; Mice, Transgenic; Mutation; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Rotarod Performance Test

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Huntington Disease / Disease Models, Animal Limits: Animals / Humans Language: En Journal: Hum Mol Genet Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2013 Type: Article

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