Inflammatory mediators alter the astrocyte transcriptome and calcium signaling elicited by multiple G-protein-coupled receptors.

Hamby, Mary E; Coppola, Giovanni; Ao, Yan; Geschwind, Daniel H; Khakh, Baljit S; Sofroniew, Michael V

Hamby, Mary E; Coppola, Giovanni; Ao, Yan; Geschwind, Daniel H; Khakh, Baljit S; Sofroniew, Michael V.

Affiliation

Hamby ME; Department of Neurobiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90095-1763, USA.

J Neurosci ; 32(42): 14489-510, 2012 Oct 17.

Article in En | MEDLINE | ID: mdl-23077035

Subject(s)

Astrocytes/metabolism; Astrocytes/pathology; Calcium Signaling/genetics; Inflammation Mediators/physiology; Receptors, G-Protein-Coupled/physiology; Transcriptome/genetics; Animals; Animals, Newborn; Cells, Cultured; Down-Regulation/genetics; Female; Interferon-gamma/physiology; Lipopolysaccharides/physiology; Male; Mice; Mice, Inbred C57BL; Receptors, G-Protein-Coupled/biosynthesis; Receptors, G-Protein-Coupled/genetics; Transforming Growth Factor beta1/physiology; Up-Regulation/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Astrocytes / Inflammation Mediators / Calcium Signaling / Receptors, G-Protein-Coupled / Transcriptome Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Neurosci Year: 2012 Type: Article Affiliation country: United States

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