Mechanistic study of broadly neutralizing human monoclonal antibodies against dengue virus that target the fusion loop.

Costin, Joshua M; Zaitseva, Elena; Kahle, Kristen M; Nicholson, Cindo O; Rowe, Dawne K; Graham, Amanda S; Bazzone, Lindsey E; Hogancamp, Greg; Figueroa Sierra, Marielys; Fong, Rachel H; Yang, Sung-Tae; Lin, Li; Robinson, James E; Doranz, Benjamin J; Chernomordik, Leonid V; Michael, Scott F; Schieffelin, John S; Isern, Sharon

Costin, Joshua M; Zaitseva, Elena; Kahle, Kristen M; Nicholson, Cindo O; Rowe, Dawne K; Graham, Amanda S; Bazzone, Lindsey E; Hogancamp, Greg; Figueroa Sierra, Marielys; Fong, Rachel H; Yang, Sung-Tae; Lin, Li; Robinson, James E; Doranz, Benjamin J; Chernomordik, Leonid V; Michael, Scott F; Schieffelin, John S; Isern, Sharon.

Affiliation

Costin JM; Department of Biological Sciences, Florida Gulf Coast University, Fort Myers, Florida, USA.

J Virol ; 87(1): 52-66, 2013 Jan.

Article in En | MEDLINE | ID: mdl-23077306

Subject(s)

Antibodies, Monoclonal/immunology; Antibodies, Neutralizing/immunology; Antibodies, Viral/immunology; Dengue Virus/immunology; Viral Envelope Proteins/immunology; Amino Acid Substitution; Animals; Antibodies, Monoclonal/isolation & purification; Antibodies, Neutralizing/isolation & purification; Antibodies, Viral/isolation & purification; Antibody-Dependent Enhancement; Cell Line; Epitope Mapping; Epitopes, B-Lymphocyte/genetics; Epitopes, B-Lymphocyte/immunology; Humans; Macaca mulatta; Mutant Proteins/immunology; Neutralization Tests

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Envelope Proteins / Dengue Virus / Antibodies, Neutralizing / Antibodies, Monoclonal / Antibodies, Viral Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Virol Year: 2013 Type: Article Affiliation country: United States

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