Progression-free survival of two cases of high-risk neuroblastoma with refractory/relapsed disease following surgery alone.
Pediatr Blood Cancer
; 60(3): 512-4, 2013 Mar.
Article
in En
| MEDLINE
| ID: mdl-23129137
ABSTRACT
Outcome for the vast majority of high-risk neuroblastoma patients with refractory or relapsed disease is dismal. We report two high-risk patients who remain progression-free for more than 113 and 18 months following the diagnosis of refractory/relapsed disease who were treated with surgery alone. Complete resolution of a refractory thoracic mass and relapsed liver nodules was observed in one patient. The refractory/relapsed disease in the second patient has remained stable. In both cases, the tumor showed histologic evidence of neuroblastoma maturation. These cases demonstrate that refractory/relapsed neuroblastoma is clinically heterogeneous and highlight the need for better biomarkers to optimize patient care.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Neoplasm Recurrence, Local
/
Neuroblastoma
Type of study:
Etiology_studies
/
Risk_factors_studies
Limits:
Child, preschool
/
Female
/
Humans
/
Infant
Language:
En
Journal:
Pediatr Blood Cancer
Journal subject:
HEMATOLOGIA
/
NEOPLASIAS
/
PEDIATRIA
Year:
2013
Type:
Article
Affiliation country:
United States