Aptamer-functionalized, ultra-small, monodisperse silica nanoconjugates for targeted dual-modal imaging of lymph nodes with metastatic tumors.

Tang, Li; Yang, Xujuan; Dobrucki, Lawrence W; Chaudhury, Isthier; Yin, Qian; Yao, Catherine; Lezmi, Stéphane; Helferich, William G; Fan, Timothy M; Cheng, Jianjun

Tang, Li; Yang, Xujuan; Dobrucki, Lawrence W; Chaudhury, Isthier; Yin, Qian; Yao, Catherine; Lezmi, Stéphane; Helferich, William G; Fan, Timothy M; Cheng, Jianjun.

Affiliation

Tang L; Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, 1304 W. Green Street, Urbana, IL 61801, USA.

Angew Chem Int Ed Engl ; 51(51): 12721-6, 2012 Dec 14.

Article in En | MEDLINE | ID: mdl-23136130

Subject(s)

Aptamers, Nucleotide/chemistry; Lymph Nodes/diagnostic imaging; Nanoconjugates/chemistry; Silicon Dioxide/chemistry; Animals; Breast Neoplasms/diagnostic imaging; Breast Neoplasms/pathology; Cell Line, Tumor; Female; Humans; Lymphatic Metastasis; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Multimodal Imaging; Nanoconjugates/ultrastructure; Positron-Emission Tomography; Rhodamines/chemistry; Spectroscopy, Near-Infrared; Tomography, X-Ray Computed; Transplantation, Heterologous

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Silicon Dioxide / Aptamers, Nucleotide / Nanoconjugates / Lymph Nodes Limits: Animals / Female / Humans Language: En Journal: Angew Chem Int Ed Engl Year: 2012 Type: Article Affiliation country: United States

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