Metatypical carcinoma of the head: a review of 312 cases.
Eur Rev Med Pharmacol Sci
; 16(14): 1915-8, 2012 Dec.
Article
in En
| MEDLINE
| ID: mdl-23242716
ABSTRACT
BACKGROUND:
Metatypical cell carcinoma (MTC) is a quite rare malignancy accounting for 5% of all non melanoma skin cancers, with features of basal cell carcinoma and squamous cell carcinoma. It can be described as coexistence of basal cell carcinoma and squamous cell carcinoma with no transition zone between them.AIM:
Our review identified a correlation between gender and MTC affected region. MATERIALS ANDMETHODS:
We performed a retrospective study of 312 consecutive patients, diagnosed for MTC localized on face and scalp. Statistical analysis was made to determinate most affected areas, gender prevalence, average age, presence of ulceration and infiltration and peripheral clearance rate.RESULTS:
A relevant difference came out between two genders. χ2 test emphasized a relation between males and the presence of carcinoma on the scalp. In addition a strong correlation between mixed subtype and ulceration was evident. A strong relation between intermediate subtype and positive surgical margin was found; this data could identify a more aggressive behavior of intermediate type.CONCLUSIONS:
In our findings an important correlation between sun exposition and this tumor was found. Moreover, due to the difficulties that can occur in preserving the aesthetic subunits in the surgical treatment of these regions, the prevention of this pathology has an important role.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Scalp
/
Skin Neoplasms
/
Facial Neoplasms
/
Carcinoma, Basal Cell
/
Carcinoma, Squamous Cell
/
Neoplasms, Complex and Mixed
/
Head and Neck Neoplasms
Type of study:
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Aged
/
Female
/
Humans
/
Male
Country/Region as subject:
Europa
Language:
En
Journal:
Eur Rev Med Pharmacol Sci
Journal subject:
FARMACOLOGIA
/
TOXICOLOGIA
Year:
2012
Type:
Article
Affiliation country:
Italy