Specific chlorination of isoquinolines by a fungal flavin-dependent halogenase.

Zeng, Jia; Lytle, Anna K; Gage, David; Johnson, Sean J; Zhan, Jixun

Zeng, Jia; Lytle, Anna K; Gage, David; Johnson, Sean J; Zhan, Jixun.

Affiliation

Zeng J; Department of Biological Engineering, Utah State University, 4105 Old Main Hill, Logan, UT 84322, USA.

Bioorg Med Chem Lett ; 23(4): 1001-3, 2013 Feb 15.

Article in En | MEDLINE | ID: mdl-23312946

Subject(s)

Flavins/chemistry; Fungal Proteins/chemistry; Hydrocarbons, Chlorinated/chemistry; Isoquinolines/chemistry; Flavins/metabolism; Fungal Proteins/metabolism; Halogenation; Hydrocarbons, Chlorinated/metabolism; Isoquinolines/metabolism; Substrate Specificity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Fungal Proteins / Flavins / Hydrocarbons, Chlorinated / Isoquinolines Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2013 Type: Article Affiliation country: United States

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