Deletion of von Hippel-Lindau protein converts renin-producing cells into erythropoietin-producing cells.

Kurt, Birguel; Paliege, Alexander; Willam, Carsten; Schwarzensteiner, Ilona; Schucht, Kathrin; Neymeyer, Hanna; Sequeira-Lopez, Maria Luisa S; Bachmann, Sebastian; Gomez, R Ariel; Eckardt, Kai-Uwe; Kurtz, Armin

Kurt, Birguel; Paliege, Alexander; Willam, Carsten; Schwarzensteiner, Ilona; Schucht, Kathrin; Neymeyer, Hanna; Sequeira-Lopez, Maria Luisa S; Bachmann, Sebastian; Gomez, R Ariel; Eckardt, Kai-Uwe; Kurtz, Armin.

Affiliation

Kurt B; Institute of Physiology, University of Regensburg, D-93053 Regensburg, Germany. birguel.kurt@vkl.uni-regensburg.de

J Am Soc Nephrol ; 24(3): 433-44, 2013 Feb.

Article in En | MEDLINE | ID: mdl-23393316

Subject(s)

Erythropoietin/biosynthesis; Kidney/metabolism; Renin/biosynthesis; Von Hippel-Lindau Tumor Suppressor Protein/metabolism; Animals; Basic Helix-Loop-Helix Transcription Factors/metabolism; Erythropoietin/genetics; Gene Targeting; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism; Juxtaglomerular Apparatus/metabolism; Juxtaglomerular Apparatus/pathology; Kidney/blood supply; Kidney/pathology; Male; Mice; Mice, Knockout; RNA, Messenger/genetics; RNA, Messenger/metabolism; Renin/genetics; Von Hippel-Lindau Tumor Suppressor Protein/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Erythropoietin / Renin / Von Hippel-Lindau Tumor Suppressor Protein / Kidney Limits: Animals Language: En Journal: J Am Soc Nephrol Journal subject: NEFROLOGIA Year: 2013 Type: Article Affiliation country: Germany

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