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Elucidation of the metabolic pathways and the resulting multiple metabolites of almorexant, a dual orexin receptor antagonist, in humans.
Dingemanse, Jasper; Hoever, Petra; Hoch, Matthias; Treiber, Alexander; Wagner-Redeker, Winfried; Miraval, Tommaso; Hopfgartner, Gérard; Shakeri-Nejad, Kasra.
Affiliation
  • Dingemanse J; Actelion Pharmaceuticals Ltd, Gewerbestrasse 16, 4123 Allschwil, Switzerland. jasper.dingemanse@actelion.com
Drug Metab Dispos ; 41(5): 1046-59, 2013 May.
Article in En | MEDLINE | ID: mdl-23431113
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Neuropeptide / Receptors, G-Protein-Coupled / Isoquinolines / Acetamides Limits: Adult / Humans / Male Language: En Journal: Drug Metab Dispos Journal subject: FARMACOLOGIA Year: 2013 Type: Article Affiliation country: Switzerland
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Neuropeptide / Receptors, G-Protein-Coupled / Isoquinolines / Acetamides Limits: Adult / Humans / Male Language: En Journal: Drug Metab Dispos Journal subject: FARMACOLOGIA Year: 2013 Type: Article Affiliation country: Switzerland