Immunity against heterosubtypic influenza virus induced by adenovirus and MVA expressing nucleoprotein and matrix protein-1.

Lambe, Teresa; Carey, John B; Li, Yuanyuan; Spencer, Alexandra J; van Laarhoven, Arjan; Mullarkey, Caitlin E; Vrdoljak, Anto; Moore, Anne C; Gilbert, Sarah C

Lambe, Teresa; Carey, John B; Li, Yuanyuan; Spencer, Alexandra J; van Laarhoven, Arjan; Mullarkey, Caitlin E; Vrdoljak, Anto; Moore, Anne C; Gilbert, Sarah C.

Affiliation

Lambe T; The Jenner Institute, University of Oxford, Oxford, United Kingdom. teresa.lambe@ndm.ox.ac.uk

Sci Rep ; 3: 1443, 2013.

Article in En | MEDLINE | ID: mdl-23485942

Subject(s)

Adenoviridae/immunology; Alphainfluenzavirus/immunology; Vaccinia virus/immunology; Adenoviridae/genetics; Administration, Intranasal; Animals; CD8-Positive T-Lymphocytes/cytology; CD8-Positive T-Lymphocytes/immunology; CD8-Positive T-Lymphocytes/metabolism; Cytokines/metabolism; Female; Genetic Vectors/genetics; Genetic Vectors/metabolism; Immunization, Secondary; Influenza Vaccines/biosynthesis; Influenza Vaccines/genetics; Influenza Vaccines/immunology; Alphainfluenzavirus/metabolism; Injections, Intradermal; Interferon-gamma/metabolism; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nucleocapsid Proteins; Orthomyxoviridae Infections/immunology; Orthomyxoviridae Infections/prevention & control; RNA-Binding Proteins/genetics; RNA-Binding Proteins/metabolism; Spleen/cytology; Spleen/metabolism; Vaccinia virus/genetics; Viral Core Proteins/genetics; Viral Core Proteins/metabolism; Viral Matrix Proteins/genetics; Viral Matrix Proteins/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vaccinia virus / Adenoviridae / Alphainfluenzavirus Language: En Journal: Sci Rep Year: 2013 Type: Article Affiliation country: United kingdom

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