Metabolomic signatures in lipid-loaded HepaRGs reveal pathways involved in steatotic progression.

Brown, Meredith V; Compton, Sarah A; Milburn, Michael V; Lawton, Kay A; Cheatham, Bentley

Brown, Meredith V; Compton, Sarah A; Milburn, Michael V; Lawton, Kay A; Cheatham, Bentley.

Affiliation

Brown MV; Metabolon, Inc., Durham, North Carolina, USA.

Obesity (Silver Spring) ; 21(12): E561-70, 2013 Dec.

Article in En | MEDLINE | ID: mdl-23512965

Subject(s)

Fatty Liver/metabolism; Metabolome; Bile Acids and Salts/metabolism; Diglycerides/metabolism; Disease Progression; Fatty Liver/pathology; HEK293 Cells; Hep G2 Cells; Humans; Insulin/metabolism; Insulin Resistance; Liver/cytology; Liver/pathology; Mitochondria/metabolism; Monoglycerides/metabolism; Non-alcoholic Fatty Liver Disease; Oleic Acid/pharmacology; Oxidative Stress; Palmitic Acid/pharmacology; Phosphorylation; Reactive Oxygen Species/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Metabolome / Fatty Liver Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Obesity (Silver Spring) Journal subject: CIENCIAS DA NUTRICAO / FISIOLOGIA / METABOLISMO Year: 2013 Type: Article Affiliation country: United States

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