G51D &#945;-synuclein mutation causes a novel parkinsonian-pyramidal syndrome.

Lesage, Suzanne; Anheim, Mathieu; Letournel, Franck; Bousset, Luc; Honoré, Aurélie; Rozas, Nelly; Pieri, Laura; Madiona, Karine; Dürr, Alexandra; Melki, Ronald; Verny, Christophe; Brice, Alexis

G51D α-synuclein mutation causes a novel parkinsonian-pyramidal syndrome.

Lesage, Suzanne; Anheim, Mathieu; Letournel, Franck; Bousset, Luc; Honoré, Aurélie; Rozas, Nelly; Pieri, Laura; Madiona, Karine; Dürr, Alexandra; Melki, Ronald; Verny, Christophe; Brice, Alexis.

Affiliation

Lesage S; Pierre and Marie Curie University-Paris 6, Research Center of the Institute for Brain and Spinal Cord, National Institute of Health and Medical Research, Paris.

Ann Neurol ; 73(4): 459-71, 2013 Apr.

Article in En | MEDLINE | ID: mdl-23526723

Subject(s)

Aspartic Acid/genetics; Blepharospasm/genetics; Family Health; Glycine/genetics; Mutation, Missense/genetics; Parkinson Disease, Secondary/genetics; alpha-Synuclein/genetics; Adult; Aged; Aged, 80 and over; Amyloid/metabolism; Amyloid/ultrastructure; Blepharospasm/pathology; Caspase 3/metabolism; DNA Mutational Analysis; Dose-Response Relationship, Drug; Female; France; Globus Pallidus/pathology; Humans; Male; Middle Aged; Neuroblastoma/pathology; Neurofilament Proteins/metabolism; Parkinson Disease, Secondary/pathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease, Secondary / Blepharospasm / Family Health / Aspartic Acid / Mutation, Missense / Alpha-Synuclein / Glycine Type of study: Etiology_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Journal: Ann Neurol Year: 2013 Type: Article

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