Caprin-1, a novel Cyr61-interacting protein, promotes osteosarcoma tumor growth and lung metastasis in mice.

Sabile, Adam A; Arlt, Matthias J E; Muff, Roman; Husmann, Knut; Hess, Daniel; Bertz, Josefine; Langsam, Bettina; Aemisegger, Caroline; Ziegler, Urs; Born, Walter; Fuchs, Bruno

Sabile, Adam A; Arlt, Matthias J E; Muff, Roman; Husmann, Knut; Hess, Daniel; Bertz, Josefine; Langsam, Bettina; Aemisegger, Caroline; Ziegler, Urs; Born, Walter; Fuchs, Bruno.

Affiliation

Sabile AA; Laboratory for Orthopedic Research, Department of Orthopedics, Balgrist University Hospital, Zurich, Switzerland. asabile@research.balgrist.ch

Biochim Biophys Acta ; 1832(8): 1173-82, 2013 Aug.

Article in En | MEDLINE | ID: mdl-23528710

Subject(s)

Bone Neoplasms/pathology; Cell Cycle Proteins/metabolism; Cysteine-Rich Protein 61/metabolism; Lung Neoplasms/secondary; Osteosarcoma/pathology; Amino Acid Sequence; Animals; Apoptosis/drug effects; Bone Neoplasms/drug therapy; Bone Neoplasms/genetics; Bone Neoplasms/metabolism; Cell Cycle Proteins/biosynthesis; Cell Cycle Proteins/genetics; Cell Line, Tumor; Cisplatin/pharmacology; Cysteine-Rich Protein 61/genetics; Humans; Lung Neoplasms/genetics; Lung Neoplasms/metabolism; Lung Neoplasms/pathology; MAP Kinase Signaling System; Mice; Mice, SCID; Molecular Sequence Data; Osteosarcoma/drug therapy; Osteosarcoma/genetics; Osteosarcoma/metabolism; Phosphorylation/genetics; Prognosis; Proto-Oncogene Proteins c-akt/genetics; Proto-Oncogene Proteins c-akt/metabolism; Transplantation, Heterologous

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone Neoplasms / Osteosarcoma / Cell Cycle Proteins / Cysteine-Rich Protein 61 / Lung Neoplasms Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Biochim Biophys Acta Year: 2013 Type: Article Affiliation country: Switzerland

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