Intrathecal administration of cyclic AMP response element-binding protein-antisense oligonucleotide attenuates neuropathic pain after peripheral nerve injury and decreases the expression of N-methyl-D-aspartic receptors in mice.

Gu, Xiaoping; Bo, Jinhua; Zhang, Wei; Sun, Xiaofeng; Zhang, Juan; Yang, Yan; Ma, Zhengliang

Gu, Xiaoping; Bo, Jinhua; Zhang, Wei; Sun, Xiaofeng; Zhang, Juan; Yang, Yan; Ma, Zhengliang.

Affiliation

Gu X; Department of Anesthesiology, Affiliated Drum Tower Hospital of Medical Department of Nanjing University, Nanjing, Jiangsu 210008, P.R. China.

Oncol Rep ; 30(1): 391-8, 2013 Jul.

Article in En | MEDLINE | ID: mdl-23633027

Subject(s)

Cyclic AMP Response Element-Binding Protein/genetics; Neuralgia/metabolism; Neuralgia/therapy; Oligonucleotides, Antisense/genetics; Receptors, N-Methyl-D-Aspartate/metabolism; Animals; Cyclic AMP Response Element-Binding Protein/metabolism; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Neuralgia/physiopathology; Oligonucleotides, Antisense/administration & dosage; Peripheral Nerve Injuries/therapy; Receptors, N-Methyl-D-Aspartate/biosynthesis; Sciatic Nerve/surgery; Sciatic Neuropathy/physiopathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligonucleotides, Antisense / Cyclic AMP Response Element-Binding Protein / Receptors, N-Methyl-D-Aspartate / Neuralgia Limits: Animals Language: En Journal: Oncol Rep Journal subject: NEOPLASIAS Year: 2013 Type: Article

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