Short-chain fatty acids activate GPR41 and GPR43 on intestinal epithelial cells to promote inflammatory responses in mice.
Gastroenterology
; 145(2): 396-406.e1-10, 2013 Aug.
Article
in En
| MEDLINE
| ID: mdl-23665276
Key words
2, 4, 6-trinitrobenzene sulfonic-acid; ATF2; C2; C3; C4; CFU; Colonic Inflammation; ECs; ERK; FITC; G-protein−coupled receptor; GPR; IL; Intestinal Barrier Leakage; KO; MAPK; Mouse Model; Pathogen; SCFAs; T-helper cell; TNBS; Th; WT; acetate; activating transcription factor 2; butyrate; colony-forming unit; epithelial cells; extracellular signal-regulated kinase; fluorescein isothiocyanate; interleukin; knock-out; mitogen-activated protein kinase; propionate; short-chain fatty acids; wild type
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Colitis
/
MAP Kinase Signaling System
/
Receptors, G-Protein-Coupled
/
Epithelial Cells
/
Fatty Acids, Volatile
/
Intestinal Mucosa
Type of study:
Prognostic_studies
Limits:
Animals
Language:
En
Journal:
Gastroenterology
Year:
2013
Type:
Article
Affiliation country:
United States